NR 507 Midterm Specific StudyGuide (Spring 2018)

Epigenetics

1. Defects in the encoding of histone-modifying proteins (Chp 6 and 12 wk 1)
2. Epigenetics and (45) its role on human development. (chp 6)
3. Totipotent cells
4. Angelman syndrome? – loss of the maternal copy of UBE3A
   

   ---

Cellular Proliferation

5. 5-Azacytidine and the(44) treatment of cancer (Chap 6 & Chp 12- wk 1)
6. the role of inactive MLH1 in the development of some forms of inherited colon cancer.
7. Effects of ethanol on neural stem cells ability to differentiate into functional neurons (chap 13,wk 1) (Chap 2
8. Inflammation as an etiology for cancer-note conditions in which this may occur 
   

   ---

Cancer

9. In terms of epigenetic modifications, the role of environmental stressors associated with development of cancer.
   

   ---

Defects in Mechanism of Defense

10. Hemolytic defects in the newborn
11. Understand the meaning of infectivity ( chap 10 )
12. Most effective treatment for HIV-
13. Defected cells of HIV
14. Signs of T-Lymphocyte deficiency 
    

    ---

Pulmonary Alterations

15. Pulmonary function tests
16. Relationship of lung compliance and (46) residual volume
17. Shifts in the oxyhemoglobin dissociation- (chap 3, 17, 34)
18. CO2 transport in the blood ( chap 34)
19. Characteristics of alveoli-
20. Arterial perfusion pressure in the lung base and
21. alveolar gas pressure in the lung base
22. How do determine the partial pressure of oxygen given the percentage of oxygen in the air and
23. (23) the barometric pressure
24. Results of increased work of breathing Know terms: Chapter 34
25. Vital capacity (VC),
26. Total lung capacity
27. Functional capacity-
28. Residual volume (RV)
29. Functional residual capacity (FRC) –
    

    ---

Play Video

Name: Jennifer Lucas
Status: Online ⬤
Classes Taken: 3878
Ratings: ⭐⭐⭐⭐⭐

Hire Me

STATUS

Renal Alterations

30. Types of nephrons and (48) their functions (chap 37)
31. Overall renal physiology-
32. Substances that are actively secreted by the renal tubules (Chap39)
33. Activation of the renin-angiotensin system
34. Glomerular filtration rate- clearance
35. Mesangial cells-
36. Renal system anatomy
37. Why plasma proteins should be absent from the urine-
38. Effects of urinary tract obstruction- hydronephrosis and a
39. (39) decreased glomerular filtration rate
40. Effect of urinary retention
41. Epispadias
42. Glomerulonephritis- ( chap 38)
43. Nephrotic syndrome- ( chap 38)